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> 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Microtubule Associated Protein 2 (MAP2) Antibody品牌 |
Leading Biology | 貨號(hào) |
AMM06395G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Microtubule Associated Protein 2 (MAP2) antibody.
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分子量 |
280 KDa
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宿主 |
Chicken
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種屬反應(yīng)性 |
Bovine, Human, Mouse, Rat
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靶點(diǎn) |
Bovine MAP2 isolated from brain by the GTP microtubule cycling method.
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基因ID |
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UniProt ID |
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總結(jié) |
Microtubules are 25nm diameter protein rods found in most kinds of eukaryotic cells. They are polymerized from a dimeric subunit made of one a subunit and one b tubulin subunit. Microtubules are associated with a family of proteins called microtubule associated proteins (MAPs), which includes the protein τ (tau) and a group of proteins referred to as MAP1, MAP2, MAP3, MAP4 and MAP5 (Kindler & Gardner 1994). MAP2 is made up of two ~280kDa apparent molecular weight bands referred to as MAP2a and MAP2b. A third lower molecular weight form, usually called MAP2c, corresponds to a pair of protein bands running at ~70kDa on SDS-PAGE gels. All these MAP2 forms are derived from a single gene by alternate transcription, and all share a C-terminal sequence which includes either three or four microtubule binding peptide sequences, which are very similar to those found in the related microtubule binding protein τ (tau). MAP2 isoforms are expressed only in neuronal cells and specifically in the perikarya and dendrites of these cells. MAP2 has been recently shown to be the specific receptor for the neurosteroid pregnenolone (Fontaine-Lenore V. et al., 2006).
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形式 |
Total IgY fraction
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IF
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稀釋方法 |
WB~~ 1:20000
IF~~ 1:2500
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別名 |
Microtubule-associated protein 2, MAP-2, MAP2
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圖像 |
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說明書 |
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數(shù)量 |
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