品牌 |
Leading Biology | 貨號 |
AMM06637G |
產品分類 |
Polyclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Neurofilament M (NF-M) antibody.
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分子量 |
145 KDa
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宿主 |
Chicken
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種屬反應性 |
Rat
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靶點 |
Preparation containing the extreme C-terminus expressed in and purified from E. Coli.
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基因ID |
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UniProt ID |
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總結 |
Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease (2).
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形式 |
Total IgY fraction
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IF
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稀釋方法 |
WB~~ 1:5000
IF~~ 1:1000
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別名 |
Neurofilament medium polypeptide, NF-M, 160 kDa neurofilament protein, Neurofilament 3, Neurofilament triplet M protein, Nefm, Nef3, Nfm
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圖像 |
Westernblot of rat cortex lysate showing specific immunolabeling of the ~ 145k NF-M protein. Immunostaining of cultured rat neurons and glia showing labeling of NF-M in red. |
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說明書 |
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數量 |
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