ALDH5A1 Antibody (CT)

APG01778G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APG01778G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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ALDH5A1 Antibody (CT)

品牌	Leading Biology	貨號(hào)	APG01778G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ALDH5A1 antibody (CT).
分子量	57215 Da
細(xì)胞定位	Antigen Cellular Localization: Mitochondrion.
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
靶點(diǎn)	ALDH5A1
亞型	Rabbit IgG
通用名	SSADH
基因ID	7915
UniProt ID	P51649
功能	Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
總結(jié)	Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH5A1 (aldehyde dehydrogenase 5 family, member A1), also known as SSDH or SSADH, is a 535 amino acid protein that localizes to the mitochondria and belongs to the aldehyde dehydrogenase family. Expressed in a variety of tissues, including liver, heart, lung, brain, kidney and placenta, ALDH5A1 is required for gamma-aminobutyric acid (GABA) recycling from the synaptic cleft. Mutations of ALDH5A1 lead to succinate semialdehyde dehydrogenase deficiency (SSADH deficiency) that is characterized by severe ataxia and by mildly retarded psychomotor development.
形式	Liquid. In PBS containing 0.02% sodium azide.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC
別名	ALDH5A1; SSADH; Succinate-semialdehyde dehydrogenase, mitochondrial; Aldehyde dehydrogenase family 5 members A1; NAD (+)-dependent succinic semialdehyde dehydrogenase.
圖像	Western blot analysis in SK-BR-3 cell lysates (35 μg/lane). Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with ALDH5A1 antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
說明書	Product Datasheet Protocol
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