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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > FKBP52/Hsp56 Antibody

FKBP52/Hsp56 Antibody

貨號 貨期 規(guī)格 / 價格 詢價
APR15993G 100 μg / ¥4950

FKBP52/Hsp56 Antibody

品牌

Leading Biology

貨號

APR15993G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FKBP52/Hsp56 antibody.

分子量

51572 Da

細(xì)胞定位

Antigen Cellular Localization: Cytoplasm, cytosol. Mitochondrion. Nucleus. Cytoplasm, cytoskeleton Note=Shuttles from mitochondria to nucleus; co-localizes in mitochondria with the glucocorticoid receptor.

宿主

Rabbit

種屬反應(yīng)性

Mouse, Rat

靶點(diǎn)

FKBP52/Hsp56

亞型

Rabbit IgG

通用名

Fkpb52

基因ID

UniProt ID

功能

Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.

總結(jié)

FKBP52 (also known as FKBP4, Hsp56, FK506 binding protein 4, p52, FKBP59) is a 55kDa peptidyl-propyl isomerase. FKBP52 catalyzes the transition between cis- and trans- proline residues which is important in immunoregulation and proper protein folding and trafficking. FKBP52 may involve in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors.

形式

Liquid

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB

別名

FKBP4, Hsp56, FK506 binding protein 4, p52, FKBP59

說明書

數(shù)量

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