全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM06647G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Neuropilin-1 antibody.
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分子量 |
103000 Da
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細胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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宿主 |
Rabbit
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種屬反應性 |
Mouse, Rat
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靶點 |
Neuropilin
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亞型 |
Rabbit IgG
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通用名 |
Nrp
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基因ID |
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UniProt ID |
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功能 |
Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, the PLGF-2 isoform of PGF, the VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis (By similarity).
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總結 |
Neuropilin 1 is a type 1 membrane-bound coreceptor to a tyrosine kinase receptor for both Vascular Endothelial Growth Factor and Semaphorin family members. Neuropilin 1 is invovled in axon growth and guidance, cell survival, migration, and invasion.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB
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別名 |
CD304 , DKFZp686A03134 , DKFZp781F1414 , NRP , NRP1 , VEGF165R , neuropilin-1
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說明書 |
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數(shù)量 |
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