ALDH3A1 Antibody (Center)

APR07057G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR07057G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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ALDH3A1 Antibody (Center)

品牌	Leading Biology	貨號(hào)	APR07057G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ALDH3A1 antibody (Center).
分子量	50395 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm.
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	254-284 aa
靶點(diǎn)	This ALDH3A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-284 amino acids from the Central region of human ALDH3A1.
亞型	Rabbit Ig
通用名	ALDH3
基因ID	218
UniProt ID	P30838
功能	ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.
總結(jié)	Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. ALDH3A1 forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. The enzyme is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, E
稀釋方法	WB~~1:1000 IHC-P~~1:10~50
別名	Aldehyde dehydrogenase, dimeric NADP-preferring, ALDHIII, Aldehyde dehydrogenase 3, Aldehyde dehydrogenase family 3 member A1, ALDH3A1, ALDH3
圖像	Anti-ALDH3A1 Antibody (Center) at 1:1000 dilution + human lung lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 50 kDa Blocking/Dilution buffer: 5% NFDM/TBST. ALDH3A1 Antibody (Center) (Cat. APR07057G) western blot analysis in A549,Daudi,Hela cell line lysates (35ug/lane).This demonstrates the ALDH3A1 antibody detected the ALDH3A1 protein (arrow). Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ALDH3A1 antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
說明書	Product Datasheet Protocol
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