DNAJA1 Antibody (C-term)

APR15757G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR15757G		100 μl / ￥4950

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DNAJA1 Antibody (C-term)

品牌	Leading Biology	貨號	APR15757G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DNAJA1 antibody (C-term).
分子量	44868 Da
細胞定位	Antigen Cellular Localization: Membrane; Lipid-anchor. Cytoplasm. Microsome. Nucleus. Cytoplasm, perinuclear region. Mitochondrion Note=Primarily associated with microsomes. A minor proportion is associated with mitochondria (By similarity). Primarily cytoplasmic. A minor proportion is associated with nuclei
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
靶點	This DNAJA1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 379-414 amino acids from the C-terminal region of human DNAJA1.
亞型	Rabbit Ig
通用名	DNAJ2, HDJ2, HSJ2, HSPF4
基因ID	3301
UniProt ID	P31689
功能	Co-chaperone for HSPA8/Hsc70 (PubMed:10816573). Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro) (PubMed:24318877). Plays a role in protein transport into mitochondria via its role as co- chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis (PubMed:14752510). Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV (PubMed:24512202).
總結(jié)	Co-chaperone of Hsc70. Seems to play a role in protein import into mitochondria.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	DnaJ homolog subfamily A member 1, DnaJ protein homolog 2, HSDJ, Heat shock 40 kDa protein 4, Heat shock protein J2, HSJ-2, Human DnaJ protein 2, hDj-2, DNAJA1, DNAJ2, HDJ2, HSJ2, HSPF4
圖像	Western blot analysis of lysates from HepG2, SK-BR-3, Raji cell line, mouse lung tissue lysate and rat PC-12 cell line (from left to right), using DNAJA1 Antibody (C-term)( APR15757G). APR15757G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
說明書	Product Datasheet Protocol
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