HUMAN-SHB(Y268) Antibody

APR16791G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR16791G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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HUMAN-SHB(Y268) Antibody

品牌	Leading Biology	貨號	APR16791G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HUMAN-SHB(Y268) antibody.
分子量	55042 Da
細胞定位	Antigen Cellular Localization: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associates with membrane lipid rafts upon TCR stimulation
宿主	Rabbit
種屬反應(yīng)性	Human
靶點	This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 250-290 amino acids from human.
亞型	Rabbit Ig
基因ID	6461
UniProt ID	Q15464
功能	Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic- FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.
總結(jié)	Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic- FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, FC, E
稀釋方法	IHC-P~~1:25 FC~~1:25 WB~~1:1000
別名	SH2 domain-containing adapter protein B, SHB
圖像	Immunohistochemical analysis of paraffin-embedded H. small intestine section using Phospho-HUMAN-SHB(Y268). ctrl( APR16791G). APR16791G was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining. Flow cytometric analysis of HepG2 cells using Phospho-HUMAN-SHB(Y268). ctrl(green, APR16791G) compared to an isotype control of rabbit IgG(blue). APR16791G was diluted at 1:25 dilution. An Alexa Fluor? 488 goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody. Western blot analysis of lysates from HepG2, Jurkat, K562, HUVEC cell line (from left to right), using SHB-Y268 Antibody( APR16791G). APR16791G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
說明書	Product Datasheet Protocol
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