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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > PSEN2(Presenilin-2 CTF subunit) Antibody (C-term)

PSEN2(Presenilin-2 CTF subunit) Antibody (C-term)

貨號 貨期 規(guī)格 / 價格 詢價
AMR09575G 100 μl / ¥4950

PSEN2(Presenilin-2 CTF subunit) Antibody (C-term)

品牌

Leading Biology

貨號

AMR09575G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PSEN2(Presenilin-2 CTF subunit) antibody (C-term).

分子量

50140 Da

細(xì)胞定位

Antigen Cellular Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein

宿主

Rabbit

種屬反應(yīng)性

Human

靶點

This PSEN2(Presenilin-2 CTF subunit) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 401-445 amino acids from the C-terminal region of human PSEN2(Presenilin-2 CTF subunit).

亞型

Rabbit Ig

通用名

AD4, PS2, PSNL2, STM2

基因ID

UniProt ID

功能

Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.

總結(jié)

Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, E

稀釋方法

IHC-P~~1:25 WB~~1:1000

別名

Presenilin-2, PS-2, 3423-, AD3LP, AD5, E5-1, STM-2, Presenilin-2 NTF subunit, Presenilin-2 CTF subunit, PSEN2, AD4, PS2, PSNL2, STM2

圖像

Immunohistochemical analysis of paraffin-embedded M.heart section using PSEN2(Presenilin-2 CTF subunit) Antibody (C-term)( AMR09575G). AMR09575G was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.

Immunohistochemical analysis of paraffin-embedded R.heart section using PSEN2(Presenilin-2 CTF subunit) Antibody (C-term)( AMR09575G). AMR09575G was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.

Immunohistochemical analysis of paraffin-embedded H.heart section using PSEN2(Presenilin-2 CTF subunit) Antibody (C-term)( AMR09575G). AMR09575G was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.

說明書

數(shù)量

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