品牌 |
Leading Biology | 貨號(hào) |
APR13478G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SOX8 antibody (Center).
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分子量 |
47314 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267}
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
225-253 aa
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靶點(diǎn) |
This SOX8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-253 amino acids from the Central region of human SOX8.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3' (By similarity).
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總結(jié) |
This gene encodes a member of the SOX (SRY-relatedHMG-box) family of transcription factors involved in the regulationof embryonic development and in the determination of the cell fate.The encoded protein may act as a transcriptional activator afterforming a protein complex with other proteins. This protein may beinvolved in brain development and function. Haploinsufficiency forthis protein may contribute to the mental retardation found inhaemoglobin H-related mental retardation (ART-16 syndrome).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Transcription factor SOX-8, SOX8
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圖像 |
SOX8 Antibody (Center) (Cat. APR13478G) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the SOX8 antibody detected the SOX8 protein (arrow). |
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說(shuō)明書(shū) |
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數(shù)量 |
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