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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > M Mlkl Antibody (C-term)

M Mlkl Antibody (C-term)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR14272G 100 μl / ¥4950

M Mlkl Antibody (C-term)

品牌

Leading Biology

貨號(hào)

APR14272G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality M Mlkl antibody (C-term).

分子量

54317 Da

細(xì)胞定位

Antigen Cellular Localization: Cytoplasm. Cell membrane. Note=Localizes to the cytoplasm and translocates to the plasma membrane on necroptosis induction.

宿主

Rabbit

種屬反應(yīng)性

Mouse

免疫原

444-472 aa

靶點(diǎn)

This Mouse Mlkl antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 444-472 amino acids from the C-terminal region of mouse Mlkl.

亞型

Rabbit Ig

基因ID

UniProt ID

功能

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

總結(jié)

The protein kinase domain is predicted to be catalytically inactive. Molecular function: protein binding. There are two isoforms.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, E

稀釋方法

WB~~1:1000

別名

Mixed lineage kinase domain-like protein, Mlkl {ECO:0000312|EMBL:AAH237551, ECO:0000312|MGI:MGI:1921818}

圖像

All lanes : Anti-Mlkl Antibody (C-term) at 1:2000 dilution Lane 1: mouse testis lysates Lane 2: mouse liver lysates Lane 3: NIH/3T3 whole cell lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 54 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

All lanes : Anti-Mlkl Antibody (C-term) at 1:2000 dilution Lane 1: NIH/3T3 whole cell lysates Lane 2: mouse spleen lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 54 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Anti-Mlkl Antibody (C-term)at 1:1000 dilution + mouse lung lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 54 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

說明書

數(shù)量

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