全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM07932G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SOCS4 antibody (Center).
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分子量 |
50623 Da
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
227-254 aa
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靶點(diǎn) |
This SOCS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the Central region of human SOCS4.
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亞型 |
Rabbit Ig
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通用名 |
SOCS7
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基因ID |
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UniProt ID |
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功能 |
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC- CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR.
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總結(jié) |
The protein encoded by this gene contains a SH2 domain anda SOCS BOX domain. The protein thus belongs to the suppressor ofcytokine signaling (SOCS), also known as STAT-induced STATinhibitor (SSI), protein family. SOCS family members are known tobe cytokine-inducible negative regulators of cytokine signaling.Two alternatively spliced transcript variants encoding the sameprotein have been found for this gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
IF~~1:10~50
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別名 |
Suppressor of cytokine signaling 4, SOCS-4, Suppressor of cytokine signaling 7, SOCS-7, SOCS4, SOCS7
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圖像 |
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說明書 |
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數(shù)量 |
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