品牌 |
Leading Biology | 貨號(hào) |
APR07201G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality UGT8 antibody (Center).
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分子量 |
61438 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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免疫原 |
366-393 aa
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靶點(diǎn) |
This UGT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-393 amino acids from the Central region of human UGT8.
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亞型 |
Rabbit Ig
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通用名 |
CGT, UGT4
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基因ID |
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UniProt ID |
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功能 |
Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system.
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總結(jié) |
Galactocerebrosides are abundant sphingolipids of themyelin membrane of the central nervous system and peripheralnervous system and are also present in small amounts in kidney. Thekey enzymatic step in the biosynthesis of galactocerebrosidesconsists of the transfer of galactose to ceramide catalyzed byUDP-galactose ceramide galactosyltransferase (CGT, EC 2.4.1.45).The enzyme encoded by the CGT gene is the first involved in complexlipid biosynthesis in the myelinating oligodendrocyte.[supplied byOMIM].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
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別名 |
2-hydroxyacylsphingosine 1-beta-galactosyltransferase, Ceramide UDP-galactosyltransferase, Cerebroside synthase, UDP-galactose-ceramide galactosyltransferase, UGT8, CGT, UGT4
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圖像 |
Anti-UGT8 antibody (Center) at 1:2000 dilution + mouse cerebellum lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 61 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Anti-UGT8 antibody (Center)at 1:2000 dilution + human heart lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 61 kDa Blocking/Dilution buffer: 5% NFDM/TBST. UGT8 antibody (Center) (Cat. APR07201G) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the UGT8 antibody detected the UGT8 protein (arrow). |
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說明書 |
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數(shù)量 |
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