品牌 |
Leading Biology | 貨號 |
APG02948G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PATL1 antibody (C-term).
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分子量 |
86850 Da
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm, P-body. Nucleus. Nucleus, PML body. Nucleus speckle. Note=Predominantly cytoplasmic. Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner Enriched in splicing speckles. Localization to nuclear foci and speckles requires active transcription. Excluded from the nucleolus
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宿主 |
Rabbit
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種屬反應性 |
Human
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免疫原 |
489-518 aa
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靶點 |
This PATL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 489-518 amino acids from the C-terminal region of human PATL1.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and replication of hepatitis C virus (HCV).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, FC, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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別名 |
Protein PAT1 homolog 1, PAT1-like protein 1, Protein PAT1 homolog b, Pat1b, hPat1b, PATL1
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圖像 |
Western blot analysis of PATL1 Antibody (C-term) (Cat. APG02948G) in HL-60 cell line lysates (35ug/lane). PATL1 (arrow) was detected using the purified Pab. PATL1 Antibody (C-term) (Cat. APG02948G) IHC analysis in formalin fixed and paraffin embedded skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PATL1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. PATL1 Antibody (C-term) (Cat. APG02948G) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
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說明書 |
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數(shù)量 |
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