品牌 |
Leading Biology | 貨號 |
APR12643G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality P2R3C antibody (N-term).
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分子量 |
53316 Da
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細胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Note=Excluded from the nucleoli. Localization is cell cycle-dependent. Localizes to the cytoplasm during cytokinesis.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
50-79 aa
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靶點 |
This P2R3C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human P2R3C.
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亞型 |
Rabbit Ig
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通用名 |
C14orf10, G5PR
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基因ID |
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UniProt ID |
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功能 |
May regulate MCM3AP phosphorylation through phosphatase recruitment. May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex. May play a role in the activation-induced cell death of B-cells.
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總結(jié) |
P2R3C may regulate MCM3AP phosphorylation through phosphatase recruitment. It may play a role in the activation-induced cell death of B-cells (By similarity).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
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別名 |
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma, Protein phosphatase subunit G5PR, Rhabdomyosarcoma antigen MU-RMS-406A/6C, PPP2R3C, C14orf10, G5PR
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圖像 |
Western blot analysis of P2R3C Antibody (N-term) (Cat. APR12643G) in Y79 cell line lysates (35ug/lane). P2R3C (arrow) was detected using the purified Pab. P2R3C Antibody (N-term) (Cat. APR12643G) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the P2R3C Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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說明書 |
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數(shù)量 |
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