全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
APR10154G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SLCO1B1 antibody (Center).
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分子量 |
76449 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Basolateral cell membrane; Multi-pass membrane protein. Note=Detected in basolateral membranes of hepatocytes
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
267-293 aa
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靶點(diǎn) |
This SLCO1B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-293 amino acids from the Central region of human SLCO1B1.
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亞型 |
Rabbit Ig
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通用名 |
LST1, OATP1B1, OATP2, OATPC, SLC21A6
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基因ID |
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UniProt ID |
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功能 |
Mediates the Na(+)-independent uptake of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. Involved in the clearance of bile acids and organic anions from the liver.
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總結(jié) |
AP9609c is a liver-specific member of the organic anion transporter family. This protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Solute carrier organic anion transporter family member 1B1, Liver-specific organic anion transporter 1, LST-1, OATP-C, Sodium-independent organic anion-transporting polypeptide 2, OATP-2, Solute carrier family 21 member 6, SLCO1B1, LST1, OATP1B1, OATP2, OATPC, SLC21A6
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圖像 |
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說(shuō)明書 |
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數(shù)量 |
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