全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR10185G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SMNDC1 antibody (N-term).
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分子量 |
26711 Da
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細胞定位 |
Antigen Cellular Localization:
Nucleus speckle. Nucleus, Cajal body. Note=Detected in nuclear speckles containing snRNP and in Cajal (coiled) bodies
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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免疫原 |
11-41 aa
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靶點 |
This SMNDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-41 amino acids from the N-terminal region of human SMNDC1.
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亞型 |
Rabbit Ig
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通用名 |
SMNR, SPF30
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基因ID |
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UniProt ID |
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功能 |
Necessary for spliceosome assembly. Overexpression causes apoptosis.
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總結(jié) |
This protein is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This protein is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, FC, E
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稀釋方法 |
WB~~1:1000
FC~~1:10~50
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別名 |
Survival of motor neuron-related-splicing factor 30, 30 kDa splicing factor SMNrp, SMN-related protein, Survival motor neuron domain-containing protein 1, SMNDC1, SMNR, SPF30
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圖像 |
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說明書 |
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數(shù)量 |
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