全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM05274G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GUSB antibody (Center).
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分子量 |
74732 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Lysosome.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
335-362 aa
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靶點(diǎn) |
This GUSB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 335-362 amino acids from the Central region of human GUSB.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Plays an important role in the degradation of dermatan and keratan sulfates.
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總結(jié) |
The GUSB gene encodes beta-glucuronidase (EC 3.2.1.31), a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans (Shipley et al., 1993 [PubMed 7680524]). It is a tetrameric glycoprotein composed of identical subunits (Oshima et al., 1987 [PubMed 3468507]). The GUSB gene is mutated in mucopolysaccharidosis type VII (MPS7; MIM 253220).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, FC, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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別名 |
Beta-glucuronidase, Beta-G1, GUSB
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圖像 |
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說明書 |
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數(shù)量 |
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