DFFA Antibody (C-term)

APR07563G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR07563G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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DFFA Antibody (C-term)

品牌	Leading Biology	貨號	APR07563G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DFFA antibody (C-term).
分子量	36522 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm.
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	304-331 aa
靶點	This DFFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-331 amino acids from the C-terminal region of human DFFA.
亞型	Rabbit Ig
通用名	DFF1, DFF45
基因ID	1676
UniProt ID	O00273
功能	Inhibitor of the caspase-activated DNase (DFF40).
總結(jié)	DFFA is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	DNA fragmentation factor subunit alpha, DNA fragmentation factor 45 kDa subunit, DFF-45, Inhibitor of CAD, ICAD, DFFA, DFF1, DFF45
圖像	Western blot analysis of DFFA (arrow) using rabbit polyclonal DFFA Antibody (C-term) (Cat. APR07563G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DFFA gene. Western blot analysis of DFFA Antibody (C-term) (Cat. APR07563G) in K562 cell line lysates (35ug/lane). DFFA (arrow) was detected using the purified Pab.
說明書	Product Datasheet Protocol
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