品牌 |
Leading Biology | 貨號 |
APR10047G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SLC25A17 antibody (N-term).
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分子量 |
34567 Da
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm. Peroxisome membrane; Multi-pass membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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免疫原 |
17-44 aa
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靶點 |
This SLC25A17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-44 amino acids from the N-terminal region of human SLC25A17.
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亞型 |
Rabbit Ig
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通用名 |
PMP34
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基因ID |
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UniProt ID |
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功能 |
Peroxisomal transporter for multiple cofactors like coenzyme A (CoA), flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN) and nucleotide adenosine monophosphate (AMP), and to a lesser extend for nicotinamide adenine dinucleotide (NAD(+)), adenosine diphosphate (ADP) and adenosine 3',5'- diphosphate (PAP). May catalyze the transport of free CoA, FAD and NAD(+) from the cytosol into the peroxisomal matrix by a counter- exchange mechanism. Inhibited by pyridoxal 5'-phosphate and bathophenanthroline in vitro.
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總結(jié) |
This protein encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, FC, E
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稀釋方法 |
WB~~1:1000
FC~~1:10~50
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別名 |
Peroxisomal membrane protein PMP34, 34 kDa peroxisomal membrane protein, Solute carrier family 25 member 17, SLC25A17, PMP34
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圖像 |
Western blot analysis of SLC25A17 Antibody (N-term) (Cat. APR10047G) in NCI-H460 cell line lysates (35ug/lane). SLC25A17 (arrow) was detected using the purified Pab. Western blot analysis of SLC25A17 Antibody (N-term) (Cat. APR10047G) in Mouse NIH-3T3 cell line lysates (35ug/lane). SLC25A17 (arrow) was detected using the purified Pab. SLC25A17 Antibody (N-term) (Cat. APR10047G) flow cytometry analysis of NCI-H460 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
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說明書 |
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數(shù)量 |
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