AK1 Antibody (N-term)

APG01639G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APG01639G		100 μl / ￥4950

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AK1 Antibody (N-term)

品牌	Leading Biology	貨號(hào)	APG01639G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AK1 antibody (N-term).
分子量	21635 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm.
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	30-59 aa
靶點(diǎn)	This AK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human AK1.
亞型	Rabbit Ig
基因ID	203
UniProt ID	P00568
功能	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
總結(jié)	Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	Adenylate kinase isoenzyme 1 {ECO:0000255\|HAMAP-Rule:MF_03171}, AK 1 {ECO:0000255\|HAMAP-Rule:MF_03171}, 2743 {ECO:0000255\|HAMAP-Rule:MF_03171}, 2746 {ECO:0000255\|HAMAP-Rule:MF_03171}, ATP-AMP transphosphorylase 1 {ECO:0000255\|HAMAP-Rule:MF_03171}, ATP:AMP phosphotransferase {ECO:0000255\|HAMAP-Rule:MF_03171}, Adenylate monophosphate kinase {ECO:0000255\|HAMAP-Rule:MF_03171}, Myokinase {ECO:0000255\|HAMAP-Rule:MF_03171}, AK1 {ECO:0000255\|HAMAP-Rule:MF_03171}
圖像	Western blot analysis of anti-AK1 Pab (Cat. APG01639G) in Jurkat cell line lysate (35ug/lane). AK1(arrow) was detected using the purified Pab. Western blot analysis of AK1 (arrow) using rabbit polyclonal AK1 Antibody (S45) (Cat. APG01639G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the AK1 gene.
說(shuō)明書	Product Datasheet Protocol
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