Creatine Kinase B Antibody (C-term)

APG02772G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APG02772G		100 μl / ￥4950

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Creatine Kinase B Antibody (C-term)

品牌	Leading Biology	貨號	APG02772G
產(chǎn)品分類	Polyclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Creatine Kinase B antibody (C-term).
分子量	42644 Da
細胞定位	Antigen Cellular Localization: Cytoplasm.
宿主	Rabbit
種屬反應性	Human, Mouse
免疫原	240-270 aa
靶點	This Creatine Kinase B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-270 amino acids from the C-terminal region of human Creatine Kinase B.
亞型	Rabbit Ig
通用名	CKBB
基因ID	1152
UniProt ID	P12277
功能	Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
總結	Creatine Kinase (CK) is a dimeric enzyme composed of either M- or B-type subunits. The resulting isoenzymes are expressed at varying levels in different tissues. CK-BB, a cytoplasmic predominantly found in brain tissues, participates in energy homeostasis, reversibly catalyzing the transfer of a phosphate group between ATP and target proteins such as a creatine phosphate. CK-BB exists in normally neglible amounts in the serum of adults, overexpression of CK-BB is associated with cancers of the breast, ovary, prostate, colon, and in small-cell lung cancer. Global assessment of changes in serum levels of CK-BB, CK-MB and CK-MM, are used as a marker for myocardial infarction.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, E
稀釋方法	WB~~1:1000
別名	Creatine kinase B-type, B-CK, Creatine kinase B chain, CKB, CKBB
圖像	Western blot analysis of CKB (arrow) using rabbit polyclonal CKB-C254 (Cat. APG02772G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CKB gene. The anti-CKB Pab (Cat. APG02772G) is used in Western blot to detect CKB in Y79 cell lysate (Lane 1) and mouse colon tissue lysate (Lane 2).
說明書	Product Datasheet Protocol
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