品牌 |
Leading Biology | 貨號 |
APR15586G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CREB3L1 antibody (C-term).
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分子量 |
57005 Da
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細胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse
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免疫原 |
481-509 aa
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靶點 |
This CREB3L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 481-509 amino acids from the C-terminal region of human CREB3L1.
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亞型 |
Rabbit Ig
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通用名 |
OASIS
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基因ID |
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UniProt ID |
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功能 |
Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE (By similarity).
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總結 |
CREB3L1 is a transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. It is specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). It may play a role in gliosis. In vitro, it binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, FC, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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別名 |
Cyclic AMP-responsive element-binding protein 3-like protein 1, cAMP-responsive element-binding protein 3-like protein 1, Old astrocyte specifically-induced substance, OASIS, Processed cyclic AMP-responsive element-binding protein 3-like protein 1, CREB3L1, OASIS
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圖像 |
Anti-CREB3L1 Antibody (C-term) at 1:8000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 57 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Western blot analysis of CREB3L1 Antibody (C-term) (Cat. APR15586G) in mouse stomach tissue lysates (35ug/lane). CREB3L1 (arrow) was detected using the purified Pab. Formalin-fixed and paraffin-embedded human prostate carcinoma with CREB3L1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
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說明書 |
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數(shù)量 |
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