品牌 |
Leading Biology | 貨號 |
AMM04845G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GNS antibody (Center S298).
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分子量 |
62082 Da
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細胞定位 |
Antigen Cellular Localization:
Lysosome.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
283-313 aa
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靶點 |
This GNS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-313 amino acids from the Central region of human GNS.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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總結(jié) |
GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, FC, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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別名 |
N-acetylglucosamine-6-sulfatase, Glucosamine-6-sulfatase, G6S, GNS
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圖像 |
Western blot analysis of GNS Antibody (Center S298) (Cat. AMM04845G) in NCI-H460, Hela, 293 cell line lysates (35ug/lane). GNS (arrow) was detected using the purified Pab. GNS Antibody (Center S298) (Cat. AMM04845G) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GNS Antibody (Center S298) for immunohistochemistry. Clinical relevance has not been evaluated. GNS Antibody (Center S298) (Cat. AMM04845G) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
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說明書 |
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數(shù)量 |
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