品牌 |
Leading Biology |
貨號(hào) |
AMM08416G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality UDB17 antibody (Center).
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分子量 |
61095 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Microsome membrane; Single- pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
119-147 aa
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靶點(diǎn) |
This UDB17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-147 amino acids from the Central region of human UDB17.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. The major substrates of this isozyme are eugenol > 4-methylumbelliferone > dihydrotestosterone (DHT) > androstane-3-alpha,17-beta-diol (3-alpha-diol) > testosterone > androsterone (ADT).
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總結(jié) |
UGT2B17 belongs to the family of UDP-glucuronosyltransferases (UGTs; EC 2.4.1.17), enzymes that catalyze the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a variety of substrates, including steroid hormones.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
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別名 |
UDP-glucuronosyltransferase 2B17, UDPGT 2B17, C19-steroid-specific UDP-glucuronosyltransferase, C19-steroid-specific UDPGT, UGT2B17
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圖像 |
Western blot analysis of UDB17 antibody (Center) (Cat. AMM08416G) in Y79 cell line lysates (35ug/lane). UDB17 (arrow) was detected using the purified Pab.
UDB17 Antibody (Center) (Cat. AMM08416G) IHC analysis in formalin fixed and paraffin embedded human Prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the UDB17 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
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說(shuō)明書(shū) |
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數(shù)量 |
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