全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
AMR09439G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PON2 antibody (Center).
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分子量 |
39397 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Membrane; Peripheral membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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免疫原 |
74-101 aa
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靶點(diǎn) |
This PON2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-101 amino acids from the Central region of human PON2.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis.
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總結(jié) |
PON2 is a member of the paraoxonase gene family,which includes three known members located adjacent to each otheron the long arm of chromosome 7. The encoded protein isubiquitously expressed in human tissues, membrane-bound, and mayact as a cellular antioxidant, protecting cells from oxidativestress. Hydrolytic activity against acylhomoserine lactones,important bacterial quorum-sensing mediators, suggests the encodedprotein may also play a role in defense responses to pathogenicbacteria. Mutations in this gene may be associated with vasculardisease and a number of quantitative phenotypes related todiabetes.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
IF~~1:10~50
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別名 |
Serum paraoxonase/arylesterase 2, PON 2, Aromatic esterase 2, A-esterase 2, Serum aryldialkylphosphatase 2, PON2
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圖像 |
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說明書 |
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數(shù)量 |
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