全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM07428G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RAB11FIP2 antibody (Center).
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分子量 |
58279 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Peripheral membrane protein. Recycling endosome membrane; Peripheral membrane protein Note=Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
345-374 aa
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靶點(diǎn) |
This RAB11FIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-374 amino acids from the Central region of human RAB11FIP2.
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亞型 |
Rabbit Ig
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通用名 |
KIAA0941
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基因ID |
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UniProt ID |
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功能 |
A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.
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總結(jié) |
RAB11FIP2 is an adapter protein that plays a role in the secretory pathway. It is thought to be important for endosome recycling and receptor-mediated endocytosis. In endosome recycling, RAB11-FIP2 regulates vesicle transport from the endosomal recycling compartment (ERC) to the plasma membrane.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, FC, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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別名 |
Rab11 family-interacting protein 2, Rab11-FIP2, NRip11, RAB11FIP2, KIAA0941
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圖像 |
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說明書 |
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數(shù)量 |
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