全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR10529G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
|
產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TPSAB1 antibody (Center).
|
||
分子量 |
30515 Da
|
||
細胞定位 |
Antigen Cellular Localization:
Secreted. Note=Released from the secretory granules upon mast cell activation.
|
||
宿主 |
Rabbit
|
||
種屬反應(yīng)性 |
Human
|
||
免疫原 |
61-87 aa
|
||
靶點 |
This TPSAB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-87 amino acids from the Central region of human TPSAB1.
|
||
亞型 |
Rabbit Ig
|
||
通用名 |
TPS1, TPS2, TPSB1
|
||
基因ID |
|||
UniProt ID |
|||
功能 |
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type.
|
||
總結(jié) |
Tryptases comprise a family of trypsin-like serineproteases, the peptidase family S1. Tryptases are enzymaticallyactive only as heparin-stabilized tetramers, and they are resistantto all known endogenous proteinase inhibitors. Several tryptasegenes are clustered on chromosome 16p13.3. These genes arecharacterized by several distinct features. They have a highlyconserved 3' UTR and contain tandem repeat sequences at the 5'flank and 3' UTR which are thought to play a role in regulation ofthe mRNA stability. These genes have an intron immediately upstreamof the initiator Met codon, which separates the site oftranscription initiation from protein coding sequence. This featureis characteristic of tryptases but is unusual in other genes. Thealleles of this gene exhibit an unusual amount of sequencevariation, such that the alleles were once thought to represent twoseparate genes, alpha and beta 1. Beta tryptases appear to be themain isoenzymes expressed in mast cells; whereas in basophils,alpha tryptases predominate. Tryptases have been implicated asmediators in the pathogenesis of asthma and other allergic andinflammatory disorders.
|
||
形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
|
||
儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
應(yīng)用 |
WB, FC, E
|
||
稀釋方法 |
WB~~1:1000
FC~~1:10~50
|
||
別名 |
Tryptase alpha/beta-1, Tryptase-1, Tryptase I, Tryptase alpha-1, TPSAB1, TPS1, TPS2, TPSB1
|
||
圖像 |
|
||
說明書 |
|||
數(shù)量 |
|
||
| 選擇 | 品牌 | 貨號 | 產(chǎn)品名稱 | 規(guī)格 | 分類 | 研究領(lǐng)域 | 說明書 | 數(shù)量 | 目錄價 | |
| 1 | Leading Biology | APR05963G | EGFR Antibody (Y1092) | 100 μl | Polyclonal Antibodies |
|
￥4950.00 | 訂購 詢價 | ||
| 2 | Leading Biology | APR03116G | BRCA1 Antibody (aa1847-1863) | 100 μl | Polyclonal Antibodies |
|
￥4950.00 | 訂購 詢價 | ||
| 3 | Leading Biology | AMM05633G | Bombesin Receptor 2 (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
|
￥6950.00 | 訂購 詢價 | ||
| 4 | Leading Biology | APR10986G | AP3B1 Antibody (aa2-14) | 50 μg | Polyclonal Antibodies |
|
￥4950.00 | 訂購 詢價 | ||
| 5 | Leading Biology | APR11512G | Bestrophin-1 (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
|
￥6950.00 | 訂購 詢價 | ||
| 6 | Leading Biology | APG01407G | A3 Adenosine Receptor Antibody | 50 μl | Polyclonal Antibodies |
|
￥6950.00 | 訂購 詢價 |
微信掃描二維碼，隨時隨地與小諾親密接觸，精彩活動，勁爆優(yōu)惠，觸手可得！
銷售-華東區(qū)