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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Cox1 Antibody

Cox1 Antibody

貨號 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APG02706G 100 μl / ¥4950

Cox1 Antibody

品牌

Leading Biology

貨號

APG02706G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Cox1 antibody.

分子量

69 65 62 56 72 KDa

細(xì)胞定位

Antigen Cellular Localization: Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein

宿主

Rabbit

種屬反應(yīng)性

Human

免疫原

568-599 aa

通用名

COX1

基因ID

UniProt ID

功能

Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.

總結(jié)

May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells.

形式

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC

稀釋方法

WB~~1:1000 IHC~~1:50-1:100

別名

Prostaglandin G/H synthase 1, Cyclooxygenase-1, COX-1, Prostaglandin H2 synthase 1, PGH synthase 1, PGHS-1, PHS 1, Prostaglandin-endoperoxide synthase 1, PTGS1, COX1

圖像

Western blot analysis of lysate from A431 cell line,using Cox1 Antibody(APG02706G). APG02706G was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.

Western blot analysis of extracts from HuvEc cells (Lane 2), using Cox1 Antibody. The lane on the left is treated with systhesized peptide.

Immunohistochemical analysis of paraffin-embedded human brain tissue using COX1 antibody .

說明書

數(shù)量

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