Caveolin-1 Antibody

APG02446G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APG02446G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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Caveolin-1 Antibody

品牌	Leading Biology	貨號(hào)	APG02446G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Caveolin-1 antibody.
分子量	20,17 KDa
細(xì)胞定位	Antigen Cellular Localization: Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein Membrane, caveola; Peripheral membrane protein. Membrane raft Note=Colocalized with DPP4 in membrane rafts. Potential hairpin- like structure in the membrane. Membrane protein of caveolae
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
免疫原	150-178 aa
通用名	CAV
基因ID	857
UniProt ID	Q03135
功能	May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3- dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
總結(jié)	May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3- dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
形式	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IF
稀釋方法	WB~~ 1:1000 IF~~1:100
別名	Caveolin-1, CAV1, CAV
圖像	Western blot analysis of lysate from Hela cell line,using Caveolin-1 Antibody(C0139). C0139 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug. Western blot analysis of extracts from HUVEC cells (Lane 1), colo cells (Lane 2) and JK cells (Lane 3), using Caveolin-1 Antibody. The lane on the left is treated with synthesized peptide. Immunofluorescence analysis of HuvEc cells, using Caveolin-1 antibody.
說明書	Product Datasheet Protocol
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