品牌 |
Leading Biology | 貨號 |
AMR09317G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PLA2G1B antibody (C-term).
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分子量 |
16360 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted. Note=secreted from pancreatic acinar cells in its inactive form
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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免疫原 |
116-145 aa
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靶點 |
This PLA2G1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-145 amino acids from the C-terminal region of human PLA2G1B.
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亞型 |
Rabbit Ig
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通用名 |
PLA2, PLA2A, PPLA2
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基因ID |
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UniProt ID |
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功能 |
PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules.
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總結(jié) |
PLA2G1B catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, FC, E
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稀釋方法 |
WB~~1:1000
FC~~1:10~50
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別名 |
Phospholipase A2, Group IB phospholipase A2, Phosphatidylcholine 2-acylhydrolase 1B, PLA2G1B, PLA2, PLA2A, PPLA2
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圖像 |
Western blot analysis of PLA2G1B Antibody (C-term) (Cat. AMR09317G) in mouse spleen tissue lysates (35ug/lane). PLA2G1B (arrow) was detected using the purified Pab. Western blot analysis of PLA2G1B (arrow) using rabbit polyclonal PLA2G1B Antibody (C-term) (Cat. AMR09317G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PLA2G1B gene. PLA2G1B Antibody (C-term) (Cat. AMR09317G) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
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說明書 |
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數(shù)量 |
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