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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Phospho-LINGO-1(LRRN6A)(S596) Antibody

Phospho-LINGO-1(LRRN6A)(S596) Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR12805G 100 μl / ¥4950

Phospho-LINGO-1(LRRN6A)(S596) Antibody

品牌

Leading Biology

貨號(hào)

APR12805G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-LINGO-1(LRRN6A)(S596) antibody.

分子量

69101 Da

細(xì)胞定位

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein

宿主

Rabbit

種屬反應(yīng)性

Human

靶點(diǎn)

This LINGO-1(LRRN6A) Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S596 of human LINGO-1(LRRN6A).

亞型

Rabbit Ig

通用名

Lern1, Lrrn6a

基因ID

UniProt ID

功能

Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (By similarity). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development.

總結(jié)

LINGO-1 (LRR and Ig domain-containing Nogo Receptor interating protein) is a nervous system-specific LRR-Ig-containing protein with an important role in CNS biology. LINGO-1 was discovered in a sequence database search for human SLIT homologs that were selectively expressed in the brain. LINGO-1 is a transmembrane protein that is a component of the Nogo-66 receptor complex. It binds NgR1 and p75 and is an additional functional componenet of the NgR1/p75 signaling complex.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

DB, E

稀釋方法

DB~~1:500

別名

Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6A, Lingo1, Lern1, Lrrn6a

圖像

Dot blot analysis of anti-Phospho-LINGO-1(LRRN6A)-pS596 Pab (Cat. APR12805G) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

說明書

數(shù)量

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