Phospho-ENT1(Slc29a1)(S254) Antibody

AMM07126G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM07126G		100 μl / ￥4950

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Phospho-ENT1(Slc29a1)(S254) Antibody

品牌	Leading Biology	貨號(hào)	AMM07126G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-ENT1(Slc29a1)(S254) antibody.
分子量	50219 Da
細(xì)胞定位	Antigen Cellular Localization: Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein Note=Predominantly localized in the basolateral membrane in polarized MDCK cells
宿主	Rabbit
種屬反應(yīng)性	Human
靶點(diǎn)	This ENT1(Slc29a1) Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S254 of human ENT1(Slc29a1).
亞型	Rabbit Ig
通用名	ENT1
基因ID	2030
UniProt ID	Q99808
功能	Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs).
總結(jié)	ENT1 is a member of the equilibrative nucleoside transporter family. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	DB, E
稀釋方法	DB~~1:500
別名	Equilibrative nucleoside transporter 1, Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter, Equilibrative NBMPR-sensitive nucleoside transporter, Nucleoside transporter, es-type, Solute carrier family 29 member 1, SLC29A1, ENT1
圖像	Dot blot analysis of anti-Phospho-ENT1(Slc29a1)-pS254 Antibody (Cat. AMM07126G) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
說(shuō)明書	Product Datasheet Protocol
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