亚洲成人aⅴ综合_男人的天堂网址在线观看_日韩国产精品欧美尤物一区二区_超级性按摩中文字幕一级不长_在线观看精品国产福利片2019_中文字幕邻居人妻_最新流露出of高能预警CDwant_粉色视频高清视频版全集_产自拍视频在线_亚洲AV永久无码精品桃花岛知道

您好,歡迎光臨安諾倫(北京)生物科技商城!
全國服務(wù)熱線:400-965-8633
關(guān)注我們
  • 會員中心
  • 會員中心
    詢價(jià)列表
    0

    最新加入的商品

    0 件商品 合計(jì):¥ 0
  • 會員中心
    購物車

    最新加入的商品

    件商品 合計(jì):¥ 0

全部產(chǎn)品分類

自主品牌
當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > PPT1 Antibody (C-term)

PPT1 Antibody (C-term)

貨號 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMR09493G 100 μl / ¥4950

PPT1 Antibody (C-term)

品牌

Leading Biology

貨號

AMR09493G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PPT1 antibody (C-term).

分子量

34193 Da

細(xì)胞定位

Antigen Cellular Localization: Lysosome.

宿主

Rabbit

種屬反應(yīng)性

Human

免疫原

269-300 aa

靶點(diǎn)

This PPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-300 amino acids from the C-terminal region of human PPT1.

亞型

Rabbit Ig

通用名

PPT

基因ID

UniProt ID

功能

Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.

總結(jié)

Palmitoyl-protein thioesterase-1 (PPT1) is a lysosomal hydrolase that removes long-chain fatty acyl groups from modified cysteine residues in proteins. Mutations in PPT1 have been found to cause the infantile form of neuronal ceroid lipofuscinosis (INCL), and an animal model has been developed.1 The deduced PPT2 protein contains 302 amino acids, including a 27-amino acid leader peptide, a sequence motif characteristic of many thioesterases and lipases, and 5 potential N-linked glycosylation sites.2 PPT2 shares 18% amino acid identity with PPT1. Northern blot analysis detected a predominant 2.0-kb PPT2 transcript in the human tissues examined, with the highest expression in skeletal muscle; variable amounts of 2.8- and 7.0-kb transcripts were also observed. Recombinant PPT2, like PPT1, possesses thioesterase activity and localizes to the lysosome. Since PPT2 could not substitute for PPT1 in correcting the metabolic defect in INCL cells and was unable to remove palmitate groups from palmitoylated proteins that are routinely used as substrates for PPT1it has been postulated that PPT2 possesses a different substrate specificity than PPT1.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, E

稀釋方法

WB~~1:1000 IHC-P~~1:50~100

別名

Palmitoyl-protein thioesterase 1, PPT-1, Palmitoyl-protein hydrolase 1, PPT1, PPT

圖像

Western blot analysis of PPT1 Antibody (C-term) (Cat. AMR09493G) in 293 cell line lysates (35ug/lane). PPT1 (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with PPT1 antibody (C-term) (Cat. AMR09493G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Western blot analysis of PPT1 (arrow) using rabbit polyclonal PPT1 Antibody (A284) (Cat. AMR09493G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PPT1 gene.

說明書

數(shù)量

相關(guān)產(chǎn)品

選擇 品牌 貨號 產(chǎn)品名稱 規(guī)格 分類 研究領(lǐng)域 說明書 數(shù)量 目錄價(jià)
1 Leading Biology APR05963G EGFR Antibody (Y1092) 100 μl Polyclonal Antibodies
¥4950.00 訂購 詢價(jià)
2 Leading Biology APR03116G BRCA1 Antibody (aa1847-1863) 100 μl Polyclonal Antibodies
¥4950.00 訂購 詢價(jià)
3 Leading Biology AMM05633G Bombesin Receptor 2 (extracellular) Antibody 50 μl Polyclonal Antibodies
¥6950.00 訂購 詢價(jià)
4 Leading Biology APR10986G AP3B1 Antibody (aa2-14) 50 μg Polyclonal Antibodies
¥4950.00 訂購 詢價(jià)
5 Leading Biology APR11512G Bestrophin-1 (extracellular) Antibody 50 μl Polyclonal Antibodies
¥6950.00 訂購 詢價(jià)
6 Leading Biology APG01407G A3 Adenosine Receptor Antibody 50 μl Polyclonal Antibodies
¥6950.00 訂購 詢價(jià)

產(chǎn)品添加成功!

購物車已有 0 件產(chǎn)品

加入詢價(jià)單成功!

詢價(jià)單已有 0 件產(chǎn)品