FDFT1 Antibody (Center)

APR07002G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR07002G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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FDFT1 Antibody (Center)

品牌	Leading Biology	貨號	APR07002G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FDFT1 antibody (Center).
分子量	48115 Da
細胞定位	Antigen Cellular Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	140-170 aa
靶點	This FDFT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-170 amino acids from the Central region of human FDFT1.
亞型	Rabbit Ig
基因ID	2222
UniProt ID	P37268
總結(jié)	FDFT1 catalyzes the first step in the cholesterol biosynthetic pathway, the conversion of trans-farnesyldiphosphate to squalene. The loss of promoter activity and response to sterols for FDFT1 is localized to a 69-bp section positioned 131 bp 5-prime to the transcription start site. Sequence analysis of this region shows that it contains a sterol regulatory element-1 (SRE1) previously identified in other sterol regulated genes and 2 putative NF1 binding sites.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, E
稀釋方法	WB~~1:1000 IHC-P~~1:50~100
別名	Squalene synthase, SQS, SS, FPP:FPP farnesyltransferase, Farnesyl-diphosphate farnesyltransferase, FDFT1
圖像	Western blot analysis of anti-FDFT1 Antibody (Center) (Cat. APR07002G) pre-incubated without(lane 1) and with(lane 2) blocking peptide (BP2417b) in A375 cell line lysate. FDFT1(arrow) was detected using the purified Pab. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with FDFT1 Antibody (Center) (Cat. APR07002G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
說明書	Product Datasheet Protocol
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