品牌 |
Leading Biology | 貨號(hào) |
APR15948G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FERMT3 antibody (N-Term).
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分子量 |
75953 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell projection, podosome. Note=Present in the F-actin surrounding ring structure of podosomes, which are specialized adhesion structures of hematopoietic cells.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Mouse
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靶點(diǎn) |
This FERMT3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 117-151 amino acids from human FERMT3.
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亞型 |
Rabbit Ig
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通用名 |
KIND3, MIG2B, URP2
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基因ID |
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UniProt ID |
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功能 |
Plays a central role in cell adhesion in hematopoietic cells. Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells. Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity).
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總結(jié) |
Plays a central role in cell adhesion in hematopoietic cells. Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells. Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:2000
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別名 |
Fermitin family homolog 3, Kindlin-3, MIG2-like protein, Unc-112-related protein 2, FERMT3, KIND3, MIG2B, URP2
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圖像 |
Anti-FERMT3 Antibody (N-Term) at 1:2000 dilution + mouse spleen lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 76 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
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說明書 |
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數(shù)量 |
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