全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM04734G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GCKR antibody (N-Term).
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分子量 |
68685 Da
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Under low glucose concentrations, GKRP associates with GCK and the inactive complex is recruited to the hepatocyte nucleus
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點 |
This GCKR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 40-72 amino acids from human GCKR.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6- phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.
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總結(jié) |
Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6- phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:2000
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別名 |
Glucokinase regulatory protein, GKRP, Glucokinase regulator, GCKR
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圖像 |
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說明書 |
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數(shù)量 |
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