TSC1 Antibody (Center T417)

APR10572G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR10572G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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TSC1 Antibody (Center T417)

品牌	Leading Biology	貨號(hào)	APR10572G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TSC1 antibody (Center T417).
分子量	129767 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Membrane; Peripheral membrane protein. Note=At steady state found in association with membranes
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	395-424 aa
靶點(diǎn)	This TSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-424 amino acids from the Central region of human TSC1.
亞型	Rabbit Ig
通用名	KIAA0243, TSC
基因ID	7248
UniProt ID	Q92574
功能	In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.
總結(jié)	In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	Hamartin, Tuberous sclerosis 1 protein, TSC1, KIAA0243, TSC
圖像	TSC1 Antibody (Center T417) (Cat. APR10572G) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the TSC1 antibody detected the TSC1 protein (arrow).
說明書	Product Datasheet Protocol
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