全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM07455G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RAB27A antibody (C-term).
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分子量 |
24868 Da
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細胞定位 |
Antigen Cellular Localization:
Membrane; Lipid-anchor. Melanosome. Late endosome. Lysosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Localizes to endosomal exocytic vesicles
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宿主 |
Rabbit
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種屬反應性 |
Human
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免疫原 |
136-164 aa
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靶點 |
This RAB27A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-164 amino acids from the C-terminal region of human RAB27A.
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亞型 |
Rabbit Ig
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通用名 |
RAB27
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基因ID |
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UniProt ID |
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功能 |
Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.
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總結 |
The protein encoded by this gene belongs to the smallGTPase superfamily, Rab family. The protein is membrane-bound andmay be involved in protein transport and small GTPase mediatedsignal transduction. Mutations in this gene are associated withGriscelli syndrome type 2. Alternative splicing occurs at thislocus and four transcript variants encoding the same protein havebeen identified.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Ras-related protein Rab-27A, Rab-27, GTP-binding protein Ram, RAB27A, RAB27
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圖像 |
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說明書 |
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數(shù)量 |
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