全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM08367G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TTPA antibody (Center).
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分子量 |
31750 Da
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm.
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宿主 |
Rabbit
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種屬反應性 |
Human
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免疫原 |
82-108 aa
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靶點 |
This TTPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-108 amino acids from the Central region of human TTPA.
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亞型 |
Rabbit Ig
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通用名 |
TPP1
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基因ID |
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UniProt ID |
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功能 |
Binds alpha-tocopherol, enhances its transfer between separate membranes, and stimulates its release from liver cells (PubMed:7887897). Binds both phosphatidylinol 3,4-bisphosphate and phosphatidylinol 4,5-bisphosphate; the resulting conformation change is important for the release of the bound alpha-tocopherol (By similarity).
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總結(jié) |
This gene encodes a soluble protein that bindsalpha-trocopherol, a form of vitamin E, with high selectivity andaffinity. This protein plays an important role in regulatingvitamin E levels in the body by transporting vitamin E betweenmembrane vesicles and facilitating the secretion of vitamin E fromhepatocytes to circulating lipoproteins. Mutations in this genecause hereditary vitamin E deficiency (ataxia with vitamin Edeficiency, AVED) and retinitis pigmentosa.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Alpha-tocopherol transfer protein, Alpha-TTP, TTPA, TPP1
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圖像 |
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說明書 |
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數(shù)量 |
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