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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > KIRREL Antibody(C-term)

KIRREL Antibody(C-term)

貨號 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR17029G 100 μl / ¥4950

KIRREL Antibody(C-term)

品牌

Leading Biology

貨號

APR17029G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KIRREL antibody(C-term).

分子量

83536 Da

細(xì)胞定位

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein. Note=Predominantly located at podocyte slit diaphragm

宿主

Rabbit

種屬反應(yīng)性

Human

免疫原

505-534 aa

靶點(diǎn)

This KIRREL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 505-534 amino acids from the C-terminal region of human KIRREL.

亞型

Rabbit Ig

通用名

KIRREL1, NEPH1

基因ID

UniProt ID

功能

Plays a significant role in the normal development and function of the glomerular permeability. Signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1 (By similarity).

總結(jié)

NEPH1 is a member of the nephrin-like protein family,which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). Thecytoplasmic domains of these proteins interact with the C terminusof podocin (NPHS2; MIM 604766), and the genes are expressed inkidney podocytes, cells involved in ensuring size- andcharge-selective ultrafiltration (Sellin et al., 2003 [PubMed12424224]).

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, E

稀釋方法

WB~~1:1000

別名

Kin of IRRE-like protein 1, Kin of irregular chiasm-like protein 1, Nephrin-like protein 1, KIRREL, KIRREL1, NEPH1

圖像

KIRREL Antibody (C-term) (Cat. APR17029G) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the KIRREL antibody detected the KIRREL protein (arrow).

說明書

數(shù)量

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