品牌 |
Leading Biology | 貨號 |
APG02022G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ATG13 antibody (Center S355.).
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分子量 |
56572 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytosol. Preautophagosomal structure. Note=Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
333-362 aa
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靶點 |
This ATG13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 333-362 amino acids from the Central region of human ATG13.
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亞型 |
Rabbit Ig
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通用名 |
KIAA0652
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基因ID |
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UniProt ID |
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功能 |
Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1- RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
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總結(jié) |
Autophagy factor required for autophagosome formation. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Autophagy-related protein 13, ATG13, KIAA0652
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圖像 |
ATG13 Antibody (Center S355.) (Cat. APG02022G) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the ATG13 antibody detected the ATG13 protein (arrow). |
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說明書 |
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數(shù)量 |
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