品牌 |
Leading Biology | 貨號 |
AMM04717G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GATM antibody(C-term).
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分子量 |
48455 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Isoform 1: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Probably attached to the outer side of the inner membrane
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
350-378 aa
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靶點(diǎn) |
This GATM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-378 amino acids from the C-terminal region of human GATM.
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亞型 |
Rabbit Ig
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通用名 |
AGAT
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基因ID |
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UniProt ID |
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功能 |
Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development. May be involved in the response to heart failure by elevating local creatine synthesis.
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總結(jié) |
This gene encodes a mitochondrial enzyme that belongs tothe amidinotransferase family. This enzyme is involved in creatinebiosynthesis, whereby it catalyzes the transfer of a guanido groupfrom L-arginine to glycine, resulting in guanidinoacetic acid, theimmediate precursor of creatine. Mutations in this gene causearginine:glycine amidinotransferase deficiency, an inborn error ofcreatine synthesis characterized by mental retardation, languageimpairment, and behavioral disorders.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Glycine amidinotransferase, mitochondrial, L-arginine:glycine amidinotransferase, Transamidinase, GATM, AGAT
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圖像 |
GATM Antibody (C-term) (Cat. AMM04717G) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the GATM antibody detected the GATM protein (arrow). |
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說明書 |
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數(shù)量 |
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