BRAP Antibody(N-term)

APR15169G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR15169G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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BRAP Antibody(N-term)

品牌	Leading Biology	貨號(hào)	APR15169G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BRAP antibody(N-term).
分子量	67305 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm.
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	66-95 aa
靶點(diǎn)	This BRAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-95 amino acids from the N-terminal region of human BRAP.
亞型	Rabbit Ig
通用名	RNF52
基因ID	8315
UniProt ID	Q7Z569
功能	Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto- polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
總結(jié)	The protein encoded by this gene was identified by itsability to bind to the nuclear localization signal of BRCA1 andother proteins. It is a cytoplasmic protein which may regulatenuclear targeting by retaining proteins with a nuclear localizationsignal in the cytoplasm.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	BRCA1-associated protein, 632-, BRAP2, Impedes mitogenic signal propagation, IMP, RING finger protein 52, Renal carcinoma antigen NY-REN-63, BRAP (HGNC:1099), RNF52
圖像	BRAP Antibody (N-term) (Cat. APR15169G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the BRAP antibody detected the BRAP protein (arrow).
說(shuō)明書	Product Datasheet Protocol
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