全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
APR16843G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ILKAP antibody(Center).
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分子量 |
42907 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
93-122 aa
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靶點(diǎn) |
This ILKAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the Central region of human ILKAP.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation.
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總結(jié) |
The protein encoded by this gene is a proteinserine/threonine phosphatase of the PP2C family. This protein caninteract with integrin-linked kinase (ILK/ILK1), a regulator ofintegrin mediated signaling, and regulate the kinase activity ofILK. Through the interaction with ILK, this protein may selectivelyaffect the signaling process of ILK-mediated glycogen synthasekinase 3 beta (GSK3beta), and thus participate in Wnt signalingpathway.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Integrin-linked kinase-associated serine/threonine phosphatase 2C, ILKAP, ILKAP
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圖像 |
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說明書 |
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數(shù)量 |
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