品牌 |
Leading Biology | 貨號(hào) |
AMM05707G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CCKAR antibody(Center).
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分子量 |
47841 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
228-257 aa
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靶點(diǎn) |
This CCKAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-257 amino acids from the Central region of human CCKAR.
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亞型 |
Rabbit Ig
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通用名 |
CCKRA
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基因ID |
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UniProt ID |
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功能 |
Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
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總結(jié) |
This gene encodes a G-protein coupled receptor that bindsnon-sulfated members of the cholecystokinin (CCK) family of peptidehormones. This receptor is a major physiologic mediator ofpancreatic enzyme secretion and smooth muscle contraction of thegallbladder and stomach. In the central and peripheral nervoussystem this receptor regulates satiety and the release ofbeta-endorphin and dopamine.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Cholecystokinin receptor type A, CCK-A receptor, CCK-AR, Cholecystokinin-1 receptor, CCK1-R, CCKAR, CCKRA
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圖像 |
CCKAR Antibody (Center)(Cat. AMM05707G) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the CCKAR antibody detected the CCKAR protein (arrow). |
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說(shuō)明書(shū) |
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數(shù)量 |
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