全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR09276G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PIG3 antibody (C-term).
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分子量 |
35536 Da
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宿主 |
Rabbit
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種屬反應性 |
Human
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免疫原 |
174-203 aa
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靶點 |
This PIG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-203 amino acids from the C-terminal region of human PIG3.
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亞型 |
Rabbit Ig
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通用名 |
PIG3
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基因ID |
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UniProt ID |
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功能 |
May be involved in the generation of reactive oxygen species (ROS). Has low NADPH-dependent beta-naphthoquinone reductase activity, with a preference for 1,2-beta-naphthoquinone over 1,4-beta-naphthoquinone. Has low NADPH-dependent diamine reductase activity (in vitro).
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總結(jié) |
The protein encoded by this gene is similar tooxidoreductases, which are enzymes involved in cellular responsesto oxidative stresses and irradiation. This gene is induced by thetumor suppressor p53 and is thought to be involved in p53-mediatedcell death. It contains a p53 consensus binding site in itspromoter region and a downstream pentanucleotide microsatellitesequence. P53 has been shown to transcriptionally activate thisgene by interacting with the downstream pentanucleotidemicrosatellite sequence. The microsatellite is polymorphic, with avarying number of pentanucleotide repeats directly correlated withthe extent of transcriptional activation by p53. It has beensuggested that the microsatellite polymorphism may be associatedwith differential susceptibility to cancer. At least two transcriptvariants encoding the same protein have been found for this gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Quinone oxidoreductase PIG3, 1---, Tumor protein p53-inducible protein 3, p53-induced gene 3 protein, TP53I3, PIG3
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圖像 |
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說明書 |
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數(shù)量 |
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