品牌 |
Leading Biology | 貨號(hào) |
AMM07668G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RREB1 antibody (C-term).
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分子量 |
181420 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus speckle
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
1398-1424 aa
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靶點(diǎn) |
This RREB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1398-1424 amino acids from the C-terminal region of human RREB1.
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亞型 |
Rabbit Ig
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通用名 |
FINB
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基因ID |
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UniProt ID |
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功能 |
Transcription factor that binds specifically to the RAS- responsive elements (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR. Potentiates the transcriptional activity of NEUROD1.
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總結(jié) |
The protein encoded by this gene is a zinc fingertranscription factor that binds to RAS-responsive elements (RREs)of gene promoters. It has been shown that the calcitonin genepromoter contains an RRE and that the encoded protein binds thereand increases expression of calcitonin, which may be involved inRas/Raf-mediated cell differentiation. Multiple transcript variantsencoding several different isoforms have been found for this gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Ras-responsive element-binding protein 1, RREB-1, Finger protein in nuclear bodies, Raf-responsive zinc finger protein LZ321, Zinc finger motif enhancer-binding protein 1, Zep-1, RREB1, FINB
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圖像 |
RREB1 Antibody (C-term) (Cat. AMM07668G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the RREB1 antibody detected the RREB1 protein (arrow). |
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說明書 |
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數(shù)量 |
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