全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR17689G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality OSCAR antibody (C-term).
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分子量 |
30481 Da
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細胞定位 |
Antigen Cellular Localization:
Isoform 1: Secreted.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
205-231 aa
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靶點 |
This OSCAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-231 amino acids from the C-terminal region of human OSCAR.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation.
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總結(jié) |
Osteoclasts are multinucleated cells that resorb bone andare essential for bone homeostasis. This gene encodes anosteoclast-associated receptor (OSCAR), which is a member of theleukocyte receptor complex (LRC) protein family that plays criticalroles in the regulation of both innate and adaptive immuneresponses. Different from the other LRC members, OSCAR expressionis detected specifically in preosteoclasts or mature osteoclasts.OSCAR may be an important bone-specific regulator of osteoclastdifferentiation. Multiple alternatively spliced transcript variantsencoding different isoforms have been found for this gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Osteoclast-associated immunoglobulin-like receptor, Osteoclast-associated receptor, hOSCAR, Polymeric immunoglobulin receptor 3, PIgR-3, PIgR3, Poly-Ig receptor 3, OSCAR
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圖像 |
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說明書 |
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數(shù)量 |
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