全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM08332G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TRHR antibody (Center).
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分子量 |
45085 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
209-238 aa
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靶點 |
This TRHR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-238 amino acids from the Central region of human TRHR.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
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總結(jié) |
Thyrotropin-releasing hormone (TRH; MIM 275120), a smallneuropeptide, is widely distributed throughout the central andperipheral nervous system as well as in extraneural tissues. Thepeptide is synthesized in the hypothalamus and transported by theportal vascular system to the anterior pituitary where it acts onthyrotropic and lactotropic cells to promote secretion of TSH andprolactin, respectively. Thyrotropin-releasing hormone receptor isa G protein-coupled receptor that activates the inositolphospholipid-calcium-protein kinase C transduction pathway upon thebinding of TRH. The TRHR gene is expressed in the thyrotrope cellsof the anterior pituitary.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Thyrotropin-releasing hormone receptor, TRH-R, Thyroliberin receptor, TRHR
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圖像 |
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說明書 |
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數(shù)量 |
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